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Tuberculosis Test

Tuberculosis (commonly shortened to TB) is an infection cused by thr bacterium mycobacterium tuberculosis , which most commonly affects the lungs (pulmonary TB) but can also affect the central nervous system(meningitis) , lymphatic system , circulatory system , genitourinary system , bones and joints.

Tuberculosis is one of the most deadly and common major infectious diseases today , infecting two billion people or one third of the world's population . nine million new cases of disease,resulting in two million deaths occur annually,mostly in the developing countries.

The diagnosis of tuberculosis is largely based on conventional approachs, which rely on clinical features,results of microscopy and culture.clinical features are not generally diagnostic and microscopy,while rapid,lacks sensitivity and specificity.culture methods are time consuming .(2 -3 weeks to obtain the results) .

An important technical advance is TB diagnosis has been the development of nucleic acid amplification(NAA) assays which will allow direct direction of tubercle bacilli as well as other mycobacteria.PCR is most commonly used for this purpose.

TBpcr (open in PDF file)


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